TY - BOOK AU - Mawdsley,Stephen E. TI - Selling Science: Polio and the Promise of Gamma Globulin T2 - Critical Issues in Health and Medicine SN - 9780813574417 AV - RA644.P9 M39 2016 U1 - 614.5/490973 23 PY - 2016///] CY - New Brunswick, NJ PB - Rutgers University Press KW - Science - Economic aspects - History - 20th century KW - Science KW - Economic aspects KW - History KW - 20th century KW - Social aspects KW - SCIENCE / General KW - bisacsh N1 - Frontmatter --; Contents --; Illustrations --; Acknowledgments --; Abbreviations --; Introduction --; Chapter 1. Forging Momentum --; Chapter 2. Building Consent for a Clinical Trial --; Chapter 3. Marketing and Mobilization --; Chapter 4. The Pilot Study --; Chapter 5. Operation Marbles and Lollipops --; Chapter 6. The National Experiment --; Notes --; Bibliography --; Index; restricted access N2 - Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously untried scale. Conducted on over 55,000 healthy children in Texas, Utah, Iowa, and Nebraska, this landmark study assessed the safety and effectiveness of a blood component, gamma globulin, to prevent paralytic polio. The value of the proposed experiment was questioned by many prominent health professionals as it harbored potential health risks, but as Mawdsley points out, compromise and coercion moved it forward. And though the trial returned dubious results, it was presented to the public as a triumph and used to justify a federally sanctioned mass immunization study on thousands of families between 1953 and 1954. Indeed, the concept, conduct, and outcome of the GG study were sold to health professionals, medical researchers, and the public at each stage. At a time when most Americans trusted scientists, their mutual encounter under the auspices of conquering disease was shaped by politics, marketing, and at times, deception. Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation UR - https://doi.org/10.36019/9780813574417 UR - https://www.degruyter.com/isbn/9780813574417 UR - https://www.degruyter.com/document/cover/isbn/9780813574417/original ER -