TY - BOOK AU - Albert,A. AU - Ayling,J.E. AU - Bacher,A. AU - Bailey,S.W. AU - Barford,P.A. AU - Baugh,ChM. AU - Baugh,Charles M. AU - Baur,R. AU - Beach,R.L. AU - Beaudette,N. AU - Bennett,C.D. AU - Bergmann,F. AU - Bieri,J.H. AU - Blair,J.A. AU - Braverman,E. AU - Brown,D.J. AU - Brown,G.M. AU - Buff,K. AU - Cenoni,E. AU - Chan,P.Y. AU - Chanarin,I. AU - Chmurzyriska,W. AU - Combepine,G. AU - Contini,C. AU - Cossins,E.A. AU - Cremer-Bartels,G. AU - Dairman,W. AU - Deits,T.L. AU - Descimon,H. AU - Donoghue,D. AU - Eggers,U. AU - Eto,I. AU - Eugster,C.H. AU - Ewers,U. AU - Fan,C.L. AU - Ferone,R. AU - Foor,F. AU - Forrest,H.S. AU - Frick,W. AU - Fujii,K. AU - Fukushima,K. AU - Gapski,G.R. AU - Gaumont,Y. AU - Ginger,C.D. AU - Goodson,S. AU - Gottlieb,R. AU - Gronenborn,A. AU - Grzelakowska-Sztabert,B. AU - Günther,H. AU - Hackstein,J.H.P. AU - Harders,H. AU - Harzer,G. AU - Heine,M.C. AU - Helfand,G.D. AU - Henderson,G.B. AU - Hirshfield,J.M. AU - Hoogsteen,K. AU - Huennekens,F.M. AU - Iten,P.X. AU - Iwai,K. AU - Iwanama,Y. AU - Jackson,R.C. AU - Jaenicke,L. AU - Kaufman,S. AU - Khalifa,E. AU - Kim,Y.H. AU - Kisliuk,R.L. AU - Kobashi,M. AU - Kulick,R.J. AU - Kwee,S. AU - Landman,M. AU - Laudani,U. AU - Leary,R.P. AU - Levene,L. AU - Lor,K.L. AU - Lumb,M. AU - Lund,H. AU - Lynn,R.K. AU - Mager,H.I.X. AU - Mailänder,B. AU - Mautner,H.G. AU - Mayumi,T. AU - McCormack,John J. AU - Mengel,R. AU - Momzikoff,A. AU - Montgomery,J.A. AU - Müller,K. AU - Nair,M.G. AU - Niethammer,D. AU - Pearson,A.J. AU - Perrault,M.M. AU - Perry,J. AU - Pfleiderer,W. AU - Piper,J.R. AU - Plaut,G.W.E. AU - Poe,M. AU - Rahat,M. AU - Reddel,R. AU - Rembold,H. AU - Richter,W. AU - Rimkus,B. AU - Rokos,H. AU - Rokos,K. AU - Rose,J.D. AU - Rowe,P.B. AU - Russel,A. AU - Rüdiger,H. AU - Sauer,H. AU - Schnepple,H. AU - Schwinck,I. AU - Scrimgeour,K.G. AU - Sengupta,P.K. AU - Sharma,R.K. AU - Shiota,T. AU - Silink,M. AU - Smith,J.H. AU - Southon,I. AU - Stelcner,S. AU - Suckling,C.J. AU - Suzuki,Y. AU - Sweeney,J.R. AU - Tamir,I. AU - Taylor,E.C. AU - Temple,C. AU - Viscontini,M. AU - Wagner,C. AU - Waxman,S. AU - Webb,S.R. AU - Weber,R. AU - Whitehead,V.M. AU - Whiteley,J.M. AU - Williams,M.N. AU - Wilmanns,W. AU - Wood,H.C.S. AU - Wrigglesworth,R. AU - Yim,J. AU - Zamierowski,M. TI - Chemistry and Biology of Pteridines: Pteridines and Folic Acid Derivatives. Proceedings of the International Symposium on Pteridines and Folic Acid Derivatives, Chemical, Biological and Clinical Aspects. T2 - Chemistry and Biology of Pteridines SN - 9783110059281 U1 - 612.01 PY - 2019///] CY - Berlin, Boston : PB - De Gruyter, KW - REFERENCE / General KW - bisacsh N1 - Frontmatter --; Preface --; Contents --; List of Contributors --; Significant Steps in the Discovery and Application of Pteridines --; Specific Inhibition of Dihydrofolate Biosynthesis - A New Approach to Chemotherapy --; Mammalian Dihydrofolate Reductase: Porcine Liver Enzyme --; Kinetic Studies of Escherichia Coli Dihydropteroate Synthetase --; Dihydropteroate Synthase: Purification by Affinity Chromatography and Mechanism of Action --; The Properties of Gamma Glutamyl Hydrolase (Conjugase) from Bovine Liver --; The Purification of Riboflavin Synthetase by Affinity Chromatography Using 7-Oxolumazines --; Interaction of Riboflavin Synthetase with Analogues of 6,7-Dimethyl-8-Ribityllumazine --; Structure-Activity Relationship Among Pteridine Derivatives and Related Quinazolines as Inhibitors of Dihydrofolate Reductases --; Spectral Studies of Thymidylate Synthetase --; Four Folate Metabolizing Enzymes of Mouse Embryo Fibroblasts and L-Cells as Tested During the Culture Cycle --; The Activity of the Cobalamine-dependent Methionine- Synthetase (5-Methyl-5, 6, 7, 8-Tetrahydrofolic Acid: Homocysteine Methyltransferase) in Rapidly Growing Human Cells and the Effect of Some Folic Acid Derivatives and Analogues --; The Role of Folate Binding Proteins in Folate Metabolism --; Transport of Folate Compounds into Mammalian and Bacterial Cells --; Transport of Folate Compounds through the Membrane of Human Lymphoblastoid Cells --; The Characterization of High Molecular Weight Complexes of Folic Acid in Mammalian Tissues --; The Enzymic Synthesis of Pterins in Escherichia Coli --; Biosynthesis of Pterins in Mammalian Systems --; The Synthesis of Pterins Catalyzed by Enzymes from Drosophila melanogaster --; Biosynthesis of Biopterin in the Intact Rat and in Mouse Neuroblastoma Cells --; Studies on the Biosynthesis of Riboflavin --; Studies on the Mechanism of Phenylalanine Hydroxylase: Detection of an Intermediate --; Effect of Pteridine Cofactor Structure on the Regulation of Phenylalanine Hydroxylase Activity --; Interrelationships between C-1 Metabolism and Photosynthesis in Euglena Gracilis --; Folate Derivatives and Patterns of C-1 Metabolism in Neurospora Crassa, Wild Type, Ser-1 and Formate Mutants --; The Biosynthesis of Folic Acid and Pteridine Cofactor (s) and its Regulation --; Reduced Pterins as Possible Mediators in Cellular Electron Transfer --; The Handling and Metabolism of Folates in the Rat and Man, with Especial Relationship to Disease --; Red Blood Cell Polyglutamyl Folates in Vitamin B12 Deficiency --; Novel Urinary Metabolites of Folic Acid in the Rat --; "Prune"/"Killer-of-Prune": A Complementary Lethal System in Drosophila Melanogaster Affecting Pteridine Metabolism --; Kynurenine as Trigger in Pterorhodin Synthesis in Ephestia Kuhniella Z. --; Growth Stimulation by 6-Phenacylisoxanthopterin and Related Compounds --; The Possible Role in Gene Regulation of an Isoxanthopterinbinding Protein from Oncopeltus Embryos --; Poly-γ-Glutamyl Chain Lengths in some Natural Folates and Contributions of Folic Acid Synthesized by Intestinal Microflora to Rat Nutrition --; Tissue-Specific Synthesis of Methotrexate Polyglutamates in the Rat --; A Convenient Synthesis of Methotrexate and Related Compounds --; Methods for the Synthesis of Folic Acid Analogs, Substituted Folic Acid Analogs, Folic Acid and Folic Acid Conjugates --; New Folate Analogs: Alterations in the C9-N10 Region --; The Synthesis and Study of 10-Thia-10-Deaza-Analogs of Pteroic Acid, Folic Acid, and of Related Compounds: The Problem of Racemization in the Cyclization of Substituted 2-Amino-3-Cyanopyrazines --; Synthesis and Properties of 5-Methyldihydrofolate --; A Coloured Oxidation Product from Tetrahydrofolate --; Pteridine Synthesis --; The 7-Azapteridines --; Enzymatic Oxidation of Pteridin-4-ones and Related Compounds --; Synthesis and Structure of Dihydro- and Tetrahydroderivatives of Pterin 6,7-Dicarboxylic Acid --; Direct Conversion of 4-Hydroxypteridines to their 4-Amino Analogs --; High Pressure Liquid Chromatography of Substituted Pteridines and Tetrahydropteridines --; Electrochemistry of Pteridines --; Pteridone Mediators in the Electrolysis of Biological Macromolecules --; Electrochemistry of 6,7-Dioxo-Pteridines --; Protonation and Covalent Hydration of Nitrogen Heterocycles - A Carbon-13 NMR Study [1] --; Reindarstellung und NMR-Spektroskopische Untersuchung von 5, 6, 7, 8-Tetrahydrofolsäure --; Sterische Wechselwirkungen in Substituierten Tetrahydropterinen --; Kinetisch-Mechanistische Untersuchungen an 5-Formyl-6, 7-Dimethyl-5, 6, 7, 8-Tetrahydropterin, 10-Formyl-Folsäure, 5,10-Methenyl-5, 6, 7, 8-Tetrahydrofolsäure und 5-Methyl-10-Formyl-5, 6, 7, 8- Tetrahydrofolsäure --; CNDO-Rechnungen an Pterin, 6, 7-Dimethyl-7, 8- Dihydropterin und 5-Formyl-6, 7-Dimethyl-5, 6, 7, 8- Tetrahydropterin [1] --; H-D Exchange in Pteridin-4-ones --; Oxidation-Reduction Properties of Pterins --; Autoxidative Conversions of Tetrahydropteridines and some Related Ringsystems --; Autoxidation of Tetrahydropterins --; Synthesis of Thiolumazine Nucleosides --; Pteridine Nucleotides, Synthesis and Enzymic Studies --; Biology of Pigmentation in Pieridae Butterflies --; The Pterins of the Pieridae and their Biosynthesis: Metabolism of D-Erythro-Neopterin and its 7, 8- Dihydro Derivative in Colias Croceus --; Occurrence and Distribution of Known Pterins in Some Species of Diptera --; Pteridines in the Mammalian Retina and Light Effects --; Les Pterines des Planctons Marins: Identification de plusieurs Dérivés chez les Algues Unicellulaires. Sur la Distribution des Pterines chez la Crustacés Copepodes --; Russupteridine --; Aurodrosopterins in Eye Colour Mutants of Drosophila Melanogaster --; New Results about Drosopterins --; Synthesis and Absolute Configuration of Sepiapterin --; Backmatter; restricted access; Issued also in print UR - https://doi.org/10.1515/9783110838053 UR - https://www.degruyter.com/isbn/9783110838053 UR - https://www.degruyter.com/document/cover/isbn/9783110838053/original ER -