TY - BOOK AU - Abou-Donia,M.M. AU - Abou-Donia,Martha M. AU - Abou-Hadeed,Khaled AU - Abramson,R.G. AU - Ahmed,Faizy AU - Akino,Miki AU - Al-Beir,A. AU - Allan,R.N. AU - Allen,J.R. AU - Anstead,G.M. AU - Appaji Rao,N. AU - Armarego,W.L.F. AU - Armarego,Wilfred L.F. AU - Armarego,Wilfred L.F. AU - Atarés,M. AU - Ayling,June E. AU - Baccanari,D.P. AU - Bacher,Adelbert AU - Bailey,Steven W. AU - Baker,D.J. AU - Baker,Dorothea J. AU - Balinska,Malgorzata AU - Ballou,David P. AU - Barford,P.A. AU - Barford,P.A. AU - Bartels,Rainer AU - Bartke,Michael AU - Bates,J. AU - Baugh,C.M. AU - Baur,Ralph AU - Beardsley,G.Peter AU - Beddell,C.R. AU - Beddell,Christopher R. AU - Bees,Lilias AU - Beifort,Marlene AU - Bellahsene,Z. AU - Bellahsene,Zina AU - Benkovic,Patricia A. AU - Benkovic,S.J. AU - Benkovic,Stephen J. AU - Berends,W. AU - Berndt,Jürgen AU - Berry,Helen K. AU - Bertino,J.R. AU - Bertino,J.R. AU - Bestwick,Richard K. AU - Bevan,A.W. AU - Birdsall,B. AU - Black,A.M. AU - Blair,J.A. AU - Blair,J.A. AU - Blair,John A. AU - Blakley,Raymond L. AU - Blankenship,D.T. AU - Bobinson,David H. AU - Bock,Lothar AU - Bodenberger,Ulrich AU - Bognar,Andrew L. AU - Bolin,J.T. AU - Bonneterre,J. AU - Bonneterre,Jacques AU - Booth,Joseph W. AU - Boyle,P.H. AU - Boyle,Peter AU - Bray,Robert C. AU - Broom,Arthur D. AU - Brown,Desmond J. AU - Brown,Gene M. AU - Brown,V.H. AU - Burge,A.S.V. AU - Burgen,A.S.V. AU - Bühler,Matthias AU - Cameron,Bobert C. AU - Campbell,Caryl L. AU - Cardesa-Garcia,J. AU - Champness,J.N. AU - Champness,J.Ν. AU - Champness,John N. AU - Chan,Joseph H. AU - Chan,M.M-S. AU - Chan,P.Y. AU - Chanarin,I. AU - Choolun,R. AU - Choteau,P. AU - Cichowiez,David J. AU - Clement,R.P. AU - Clore,G.M. AU - Cocco,Lennie AU - Cody,Vivian AU - Collins,Timothy D. AU - Cook,Robert J. AU - Cooper,Bernard A. AU - Corrocher,Roberto AU - Cossins,E.A. AU - Cotton,R.G.H. AU - Cotton,Richard G.H. AU - Coward,J.Κ. AU - Coward,James K. AU - Craig,G. AU - Curtius,H.-Ch AU - Daluge,Susan AU - Daniels,A.J. AU - Daniels,Alejandro J. AU - Danks,David M. AU - Dann,J.G. AU - Daubner,S.Colette AU - Dautrevaux,Michel AU - DeBrosse,Charles W. AU - DeGraw,J.I. AU - DeJarnette,Elaine AU - Deacon,Rosemary AU - Delcamp,T.J. AU - Demaille,Alain AU - Deschenes,R. AU - Dhondt,J.-L. AU - Dhondt,Jean-Louis AU - Diddens,Heyke AU - Doig,M.T. AU - Dolores Real,Maria AU - Dorsett,D. AU - Dow,Jocelyn AU - Doyle,Paul M. AU - Duch,David S. AU - Dunlap,R.Bruce AU - Dwivedi,Chandra M. AU - Eggar,C. AU - Elstner AU - Elwell,Lynn P. AU - Erbe,Richard W. AU - Farriaux,J.P. AU - Farriaux,Jean-Pierre AU - Feeney,J. AU - Ferone,R. AU - Ferone,Robert AU - Ferré,Juan AU - Filman,D.J. AU - Fink,Michael AU - Fink,Rita AU - Firgaira,Frank A. AU - Floss,Heinz G. AU - Fonda,Susan AU - Freisheim,J.H. AU - Freisheim,J.H. AU - Frisius,Hildegard AU - Fuchs,D. AU - Fuchs,Dietmar AU - Galivan,John AU - Gaumont,Y. AU - Geddes,A.J. AU - Gerisch,Günther AU - Ghisla,Sandro AU - Goldman,Daniel A. AU - Goodford,P.J. AU - Goodford,Peter J. AU - Grimshaw,C.E. AU - Gronenborn,A. AU - Grossowicz,Nathan AU - Grzelakowska-Sztabert,Barbara AU - Gröbner,Peter AU - Guest,A.E. AU - Hainline,Bryan E. AU - Ham,Ulrike AU - Hamrell,Michael R. AU - Hanlon,M.H. AU - Hansen,Steen Ingemann AU - Harding,Nigel AU - Harrington,Peter J. AU - Hasegawa,Hiroyuki AU - Hausen,A. AU - Hausen,Arno AU - Hausen,Α. AU - Hawkes,Timothy R. AU - Hearl,W.G. AU - Heckel,Armin AU - Heintel,D. AU - Henderson,G.B. AU - Herlin,Christophe AU - Hillman,Robert S. AU - Hilton,Jack H. AU - Holm,Jan AU - Hopkins,Sam AU - Hsieh,Monica AU - Hsieh,P. AU - Huber,Ch AU - Huennekens,F.M. AU - Hyde,E.I. AU - Hyde,Richard M. AU - Häusermann,M. AU - Hübsch,Walter AU - Hüfner,Michael AU - Ichiyama,Arata AU - Inoue,Fumio AU - Inoue,Kayo AU - Iqbal,M.Perwaiz AU - Iwai,Kazuo AU - Jackson,Robert C. AU - Jacobsen,D.W. AU - Jacobson,K.Bruce AU - Jastreboff,Malgorzata AU - Johnson,Jean L. AU - Jongejan,J.A. AU - Kapatos,Gregory AU - Karasik,M. AU - Kassan,Sharon AU - Katoh,S. AU - Kaufman,S. AU - Kaufman,Seymour AU - Keating,S. AU - Keller,Paul J. AU - Kelly,L.F. AU - Kempton,R.J. AU - Kfdzierska,Barbara AU - King,F.V. AU - Kisliuk,R.L. AU - Kisliuk,R.L. AU - Kisliuk,Roy L. AU - Kisthard,Holly AU - Klein Amy,Nancy AU - Kohashi,M. AU - Kohashi,Masahiro AU - Kozloff,L.M. AU - Kočevar,Marijan AU - Kraut,J. AU - Kumar,A .A. AU - Kumar,A.A. AU - Kuyper,L.F. AU - Kuyper,Lee F. AU - Kölb,Hans-Jochen AU - Lamey,Philip AU - Largilliere,C. AU - Lasser,Gerald W. AU - Lazarus,Robert A. AU - Le Van,Quang AU - Leach,M.J. AU - Leeming,R.J. AU - Lefebvre,Jean AU - Leimbacher,W. AU - Levine,Robert A. AU - Lewis,Garry P. AU - Lockhart,Ronan AU - Loidl,Peter AU - London,Robert E. AU - Lovenberg,Walter AU - Lue-Shing,Helena AU - Lumb,M. AU - Lut,Hermann AU - Lute,M. AU - Lyall,William J.S. AU - Lyngbye,Jǿrgen AU - Maclntyre,Mary-Frances AU - Mager,H.I.X. AU - Maley,Frank AU - Maley,G.F. AU - Maley,Gladys F. AU - Mandelbaum-Shavit,Frederika AU - Mangum,M. AU - Margreiter,R. AU - Mark,James E. AU - Masada,Masahiro AU - Mathews,Christopher K. AU - Matsuo,Nobutake AU - Matsuura,Sadao AU - Matthews,D.A. AU - Matthews,Rowena G. AU - Mazda,Toshio AU - McCairns,E. AU - McGing,P. AU - McGuire,J.J. AU - McMartin,Kenneth E. AU - Miller,A.A. AU - Miller,Jeffrey B. AU - Milstien,S. AU - Mizokami,Takashi AU - Moffett,Ginnie L. AU - Molloy,A. AU - Montgomery,John A. AU - Morar,C. AU - Mueller,W.Thomas AU - Ménsua,José Luis AU - Nagatsu,Ikuko AU - Nagatsu,Toshiharu AU - Nair,C.P.P. AU - Nair,M.G. AU - Nair,M.G. AU - Nakazawa,Nobuhiko AU - Narasimha Rao,D. AU - Nayyir-Mazhir,R. AU - Nichol,C.A. AU - Nichol,Charles A. AU - Nicholson,Sidney H. AU - Niederwieser,A. AU - Nielsen,Peter AU - Niethammer,Dietrich AU - Noel,C. AU - Noronha,J.M. AU - Norrington,F.E. AU - North,A.C.T. AU - O\x27Donnell,R.A. AU - Oates,G.D. AU - Ogawa,Hiroshi AU - Pallai,Michele AU - Parniak,Michael AU - Paterson,Richard A. AU - Paterson,S.J. AU - Paton,Duncan R. AU - Paur,Eva AU - Pendergast,William AU - Perry,Janet AU - Peterson,Darrell AU - Pfleiderer,Wolfgang AU - Pheasant,A.E. AU - Pheasant,Α.E. AU - Piper,W.N. AU - Potterton,E.A. AU - Priest,D.G. AU - Purohit,Sarla AU - Quadros,E.T. AU - Rabinowitz,Jesse C. AU - Rajagopalan,Κ.V. AU - Randies,David AU - Rao,Κ.N. AU - Redweik,U. AU - Reibnegger,G. AU - Reibnegger,Gilbert AU - Reizer,Jonathan AU - Riegelhaupt,Rona AU - Roberts,G.C.K. AU - Roberts,Gordon C.K. AU - Rode,Wojciech AU - Rokos,Hartmut AU - Rokos,Katharina AU - Roland,S. AU - Rosenblatt,David S. AU - Rosowsky,A. AU - Rosowsky,Andre AU - Rosowsky,Andrew AU - Roth,B. AU - Roth,Barbara AU - Rothenberg,Sheldon AU - Rowe,P.B. AU - Rowe,Peter B. AU - Rozmyslovicz,Mary K. AU - Sadewasser,D. AU - Said,Hamid M. AU - Sakate,Sakae AU - Saleh,A.M. AU - Samsonoff,William AU - Sargent,R.Geoffrey AU - Sauer,D. AU - Sauer,Hansjörg AU - Sawada,Makoto AU - Scanlon,Kevin J. AU - Schalhorn,Andreas AU - Schirch,LaVerne AU - Schlingraann,Gerhard AU - Schreiber,C. AU - Schwalbe,Carl H. AU - Schweiger,Manfred AU - Scott,J.M. AU - Seydel,J.K. AU - Shane,Barry AU - Shapiro,Howard M. AU - Shapiro,Thomas E. AU - Shinozuka,Kazuo AU - Sikora,Ewa AU - Silva,Francisco AU - Singer,S.C. AU - Sirotnak,F.M. AU - Sirotnak,F.M. AU - Slieker,Lawrence J. AU - Smith,Gary K. AU - Smith,P.L. AU - Smithwick,A. AU - Spielberger,M. AU - Spiro,Craig AU - Srinivasan,Ananthachari AU - Stammers,D.K. AU - Stammers,David K. AU - Stanovnik,Branko AU - Staudenmann,W. AU - Steinberg,Stephen AU - Stokstad,E.L.Robert AU - Stokstad,E.L.R. AU - Stone,D. AU - Strum,Williamson B. AU - Stupp-Poutot,Gabriele AU - Stäben,Chuck AU - Suckling,C.J. AU - Suckling,Colin J. AU - Sueoka,T. AU - Sugimoto,Takashi AU - Suresh,M.R. AU - Susten,S.S. AU - Szakolcai,Akos AU - Tagawa,H. AU - Talente,Edward AU - Tang,Kuo-Chang AU - Tansik,R. AU - Taylor,Edward C. AU - Temple,Carroll AU - Tišler,Miha AU - Tornita,Kazuhiro AU - Tse,J. AU - Tseng,Chi-Ping AU - Tsusue,Motoo AU - Vanhille,P. AU - Vanoni,Maria A. AU - Vestal,K. AU - Vie,M.Claude AU - Visser,K. AU - Vitols,Κ.S. AU - Viveros,O.H. AU - Viveros,O.Humberto AU - Volz,Κ.W. AU - Wagner,Conrad AU - Wang,Jin-Chen C. AU - Wang,M. AU - Waring,Paul AU - Watkins,David AU - Watson,J.E. AU - Waxman,S. AU - Waxman,Samuel AU - Webber,Stephanie AU - Weir,D.G. AU - Welsh,William J. AU - Wetzel,GUnter AU - Whitburn,S.B. AU - Whitehead,V.Michael AU - Whiteley,J.M. AU - Whiteley,John M. AU - Wick,Michael AU - Wiederrecht,Gregory J. AU - Wilgus,Harvey AU - Wilmanns,Wolfgang AU - Wilson,S.P. AU - Wobbe,C.R. AU - Wood,Hamish C.S. AU - Wood,Hamish C.S. AU - Wright,J.E. AU - Wright,Joel E. AU - Wächter,H. AU - Wächter,Helmut AU - Yamada,S. AU - Yamaguchi,Tokio AU - Yanagisawa,Mariko AU - Yim,John J. AU - Yoshida,Takeo AU - Yoshioka,Shin\x27ichi AU - Young,Douglas W. AU - Zakrzewski,Sigmund F. AU - Ziegler,Irmgard AU - Ζieger,Irmgard AU - Ζ¡eger,Irmgard TI - Chemistry and Biology of Pteridines: Pteridines and Folic Acid Derivatives. Proceedings of the International Symposium on Pteridines and Folic Acid Derivatives, Chemical, Biological and Clinical Aspects. T2 - Chemistry and Biology of Pteridines SN - 9783110085600 U1 - 612.3 PY - 2015///] CY - Berlin, Boston : PB - De Gruyter, KW - Folic Acid KW - metabolism KW - Congresses KW - Folic acid KW - Pteridines KW - Folsäure KW - Pteridine KW - REFERENCE / General KW - bisacsh N1 - Frontmatter --; Preface --; ACKNOWLEDGEMENTS --; PARTICIPANTS --; Contents --; The Gowland Hopkins Lecture: Transport of Folate and Pterin Compounds --; Chemical Aspects (1) --; Scottish International Education Trust Lecture: Synthetic Methods in Pteridine Chemistry: Some Applications to Pteridine Natural Products --; Synthesis, Chemical and Enzymatic Properties, and Therapeutic Potential of 6,6-Disubstituted Tetrahydroand Quinoid-Dihydro-Pterins --; The Structure of Quinonoid Dihydropterins [2-Amino-7,8(6H)-Dihydropteridin-4-ones] --; Some Simple s-Triazolopteridines --; Linear Tricyclic Analogs of Pteridines --; Reactions of Furazano [3,4-djPyrimidines and their Application to Pteridine Synthesis --; Syntheses of some Blocked 7,8-Dihydropteridines --; Synthesis of Chiral Reduced Pteridine Coenzymes --; Report on Discussions --; Chemical Aspects (2) --; Reactivity of Pteridines --; Synthesis and Antitumor Activity of 10-Deazaminopterins --; Synthesis and Biological Activity of 5-Deazafolic Acid and 5-Deazaaminopterin --; The Nor-Analogues of Folic Acid --; Report on Discussions --; Neurochemical and Clinical Aspects --; Metabolism of Pteridine Cofactors in Neurochemistry --; Pteridines in Cancer and Other Diseases --; Dihydropteridine Reductase Activity in Human Breast Cancer. Studies of 580 Cases and Correlations with Hormone Receptors and Cellular Typing --; A Critical Appraisal of Methods for the Quantitative Analysis of Tetrahydrobiopterin, Dihydrobiopterin and Biopterin in Human Urine, Serum and CSE --; Inhibition of Pterin Biosynthesis in the Adrenergic Neuroblastoma N1E115 by Tetrahydrobiopterin and Folate --; Penetration of Reduced Pterins into Rat Brain: Effect on Biogenic Amine Synthesis --; Neopterin Deficiency (GTP Cyclohydrolase I Deficiency), a New Variant of Hyperphenylalaninemia --; Folate Pathways in Cells from Fragile X Syndrome Patients and Carriers --; Report on Discussions --; Enzymology --; The Interaction of Substrates and Inhibitors with Dihydrofolate Reductase --; Catalytic Site of Dihydrofolate Reductase --; Structure, Function and Affinity Labelling Studies of Dihydrofolate Reductase --; Methylene Tetrahydrofoíate Reductase: Studies in a Human Mutant and Mammalian Liver --; Studies on Methylenetetrahydrofolate Reductase from Pig Liver: Catalytic Mechanism and Regulation by Adenosylmethionine --; Role of Methylenetetrahydrofolic Acid Reductase in Regulation of Folic Acid Metabolism and its Relation to the Methyl Trap Hypothesis --; The Mechanism of Action of the Transformylase Enzymes --; Folypolyglutamate Synthesis in Neurospora Crassa --; Report on Discussions --; Clinical Aspects: Cancer --; Folates and Cancer Chemotherapy --; Inability to Increase the Mobilisation of Liver Folates During Folate Deficiency Suggesting that this and Other Organs do not act as a Potential Folate Store for Marrow and Other Rapidly Proliferating Cells --; A High Molecular Weight Nonfunctional Immunoreactive Form of Dihydrofolate Reductase in L1210 Leukaemia Cells --; Further Characterization of the Pterdine Binding Variant of Alphas-Acid Glycoprotein, Accumulated in the Blood of Patients with Malignant Diseases --; Structure-Activity Relationships among 5-Substituted Lipophilic Diaminopyrimidine Antineoplastic Antifolates --; Attempts to Design Inhibitors of Dihydrofolate Reductase Using Interactive Computer Graphics with Real Time Energy Calculations --; Control of Methotrexate Polyglutamate Synthesis in Cultured Rat Hepatoma Cells --; Differential Effects of Methotrexate or Fluorodeoxyuridine upon Mitochondrial and Cellular Nucleotide Pools --; Report on Discussions --; Bioorganic Chemistry and Enzymology --; Chemical Mechanisms in the Action of Pteridine Coenzymes --; Irreversible Inactivation of Rat Liver Phenylalanine Hydroxylase by Reaction with (6S)-L-Erythro-Tetrahydrobiopterin --; p-Azidophenylalanine: A Potential Photoaffinity Probe for Rat-Liver Phenylalanine Hydroxylase --; Pyrimidine Models for the Cofactor of Phenylalanine Hydroxylase --; Activation of Molecular Oxygen by Tetrahydropterin Monooxygenases --; Mechanistic Studies on Phenylalanine Hydroxylase: Structural Determination of the Tetrahydropterin Intermediates --; Properties of Thymidylate Synthase from Streptococcus Faecium --; Cloning the Gene for Eukaryotic C1-THF Synthase --; Report on Discussions --; Biochemistry and Biology --; The Enzymatic Synthesis of the Drosopterins: Identification of a Pyrimidodiazepine as an Intermediate --; The Common Precursor of Sepiapterin and Drosopterin in Drosophila: Enzymatic and Chemical Synthesis --; The Common Precursor of Sepiapterin and Drosopterin in Drosophila: Enzymatic and Chemical Synthesis --; The Role of Pteridines in Regulation of Growth --; Evidence for a Folate Bound to Rat Hepatic Uroporphyrinogen III Cosynthase and its Role in the Biosynthesis of Heme --; Report on Discussions --; Presented Papers --; Aerobic Oxidation of 5,6,7,8-Tetrahydroneopterin --; The Conformations of 7,8 (6H)-Dihydropterin Substrates and the Activity of Dihydropteridine Reductase (E.C.1.6.99.10) --; Dihydrofolate Reductase: The Stereochemistry of Inhibitor Selectivity --; Synthesis of an 8-Deaza Analog of the Intermediate in the Thymidylate Synthetase Reaction (1) --; The Synthesis of Analogs of Pteroylglatamyl-y-Phosphate as Potential Inhibitors of Folylpolyglutamate Synthetase --; Synthesis and Activity of 8,10-Dideazaminopterin --; CNDO/2 Molecular Orbital Calculations on the Antifolate DAMP and Some of its Analogues: Conformational Characteristics --; Fluorescent Analogues of Methotrexate as Probes for Folate Antagonist Molecular Receptors --; Dihydrofolate Reductase Overproduction Identified by Flow Cytometry Using a Fluorescent Methotrexate Analogue --; New Syntheses and Transformations of Some Pteridines and Pteridine 3-Oxides --; Photooxidation of Mercaptopteridines --; Reactivity of 6,7-Dichloro-1, 3-Dimethyllumazine --; Synthesis, Reactivity and Properties of 8-Substituted 2-Thio- and 2,4-Dithiolumazines --; The Activity of Sulfonamide-Substituted Benzylpyrimidines Against Dihydropteroate Synthase, Dihydrofolate Reductase, and Bacterial Cell Cultures --; Structural Studies of Antifolate Drugs --; Isolation and Characterization of a Novel Folate Antagonist --; Synthesis and Biological Properties of the S-8 Analog of 7,8-Dihydropteridinealcohol --; Synthesis of Dihydrobiopterin from Dihydroneopterin Triphosphate in Rat Tissues and Human Blood Corpuscles: Diagnosis of Atypical Phenylketonuria due to Biopterin Deficiency by Assay of an Enzyme Involved in the Synthesis --; Stereospecific Enzyme Mediated Syntheses of Tetrahydrofolate Derivatives --; Immobilization of Dihydrofolate Reductase from Amethopterin Resistant Lactobacillus Casei --; X-Ray Studies of the Binding of Trimethoprim, Methotrexate, Pyrimethamine and Two Trimethoprim Analogues to Bacterial Dihydrofolate Reductase --; A New Spectrophotometry Method for the Assessment of Tight Binding Benzyldiaminopyrimidine Inhibitors of Dihydrofolate Reductase --; Two Interconverting Conformers of a Drug-Receptor Complex: The Lactobacillus Casei Dihydrofolate Reductase-NADP+ - Trimethoprim Complex --; Multiple Conformations of the Dihydrofolate Reductase- Folate-NADP+ Complex --; The Three-Dimensional Structure of Mouse L1210 Dihydrofolate Reductase --; Isolation and Amino Acid Sequence Studies of Dihydrofolate Reductase from Neisseria Gonorrhoeae --; Purification of 7,8-Dihydropteroate-Synthetase from E. Coli by Affinity- and Hydrophobic Interaction Chromatography --; Isolation and Characterization of an E.; Coli Mutant Affected in Dihydrofolate- and Folylpolyglutamate- Synthetase --; Purification and Properties of 5-Formyltetrahydrofolate Cyclodehydrase from Rabbit Liver --; Structural Studies on Formyl-Methenyl-Methylene Tetrahydrofolate Synthetase from Rabbit Liver --; Utilization of Folate Polyglutamate for Growth by Lactobacillus Casei --; Folate and Folate Enzymes as Structural Components of Bacteriophage Particles --; Studies on the Substrate Specificity of Mammalian Folylpolyglutamate Synthetase --; Properties of Corynebacterium Species Dihydrofolate Synthetase-Folylpolyglutamate Synthetase --; Purification and Characterization of Folylpolyglutamate Synthetase from Lactobacillus Casei and Hog Liver --; The Molybdenum Cofactor from Xanthine Oxidase: Quantitative Assay of the Molybdenum Cofactor by Activation of Nitrate Reductase Activity in Extracts of the Nit-1 Mutant of Neurospora crassa --; Structural Studies of Calf Thymus Thymidylate Synthase --; A Comparison of the T-Even Phage Induced and Escherichia Coli Thymidylate Synthases --; Thermophilicity of Dihydrofolate Reductase and Thymidylate Synthetase from a Thermophilic Microorganism --; Chemical Characterization of Two Folate-Binding Proteins from Mitochondria: Dimethylglycine Dehydrogenase and Sarcosine Dehydrogenase --; Allosteric Mung Bean (Vigna radiata) Serine Hydroxylmethyl-Transferase --; Comparative Study of the Eye Colour Mutants of Drosophila Melanogaster: Quantification of the Eye-Pigments and Related Metabolites --; Studies on Sepialumazine, the Characteristic Larval Integument Pigment of the Bombyx Mori Kiuki Mutant --; Macromolecular Regulation of Sepiapterin and Drosopterin Synthesis in the Purple Mutant of Drosophila --; The Hydroxylation of Phenylpropanoids by Euglena gracilis : Role of Pteridines --; Studies with Old Yellow Enzyme, Reconstitution with Lumazine Analogs as Coenzyme --; Biosynthesis of Riboflavin --; Biosynthesis of Riboflavin --; Metabolism and Function of Pterin Compounds in Seed Germination --; Thymidylate Synthetase During Proliferation and Differentiation of Physarum polycephalum --; Influence of Vitamin B12 on Folate Metabolism in Lactobacillus Leichmannii --; High-Affinity Binding of Folate to a Small and Large Molecular Size Protein from Human Milk --; High-Affinity Folate Binding in Leukocytes from Normal Subjects Displays Positive Cooperativity, and the Affinity Depends on the Protein Concentration --; Characteristics of 5-Methyltetrahydrofolate Binding to the Folate-Binding Protein from Cow's Whey --; Interactions of Folate-Dependent Enzymes of DNA Precursor Metabolism in T4 Phage-Infected Bacteria --; The Regulation of Biopterin Biosynthesis in the Rat --; Biosynthesis of Tetrahydrobiopterin in Mammalian Tissues by De Novo and Salvage Pathways --; Perspectives on Tetrahydrobiopterin Biosynthesis in Mammals --; Human Dihydropteridine Reductase (DHPR) Deficiency --; Coordinate Regulation of Guanosine Triphosphate Cyclohydrolase and Tetrahydrobiopterin in Adrenal Medullary Chromaffin Cells --; Regulation of Adrenocortical Guanosine Triphosphate Cyclohydrolase and Tetrahydrobiopterin in Normal and Spontaneously Hypertensive Rats --; Inhibition of Brain Sepiapterin Reductase by a Catecholamine and an Indoleamine --; Mouse Mastocytoma Tryptophan Hydroxylase: Role of Iron and Catalase in the Expression of Enzyme Activity after Activation by Anaerobic Preincubation with Dithiothreitol --; Folic Acid Induced Kindling in Rats: Changes in Brain Amino Acids --; Impaired Pteroylpolyglutamate Synthesis in the Cobalamin-Inactivated Rat --; A Radioimmunoassay for Determination of D-Erythro- Neopterin --; Radioimmunoassay for Neopterin in Body Fluid and Tissues --; A Specific Antiserum Against Tetrahydrobiopterin: Its Preparation and Application to Immunohistochemistry --; Speculation on the Mechanism of Therapeutic Action of Tetrahydrobiopterin in Human Disease --; Correlation of Tetrahydrobiopterin Content and Guanosine Triphosphate Cyclohydrolase Activity in Cells and Tissues --; Unconjugated Pteridines in Human Physiological Fluids. Normal and Pathological Profiles --; Biopterin and Phenylalanine Metabolism During Early Liver Regeneration --; GTP-Cyclohydrolase Activities in Rat Liver --; Phenylalanine Hydroxylase Assay Using Biopterin and Synthetic Pteridine --; Dihydropteridine Reductase Levels in Human Normal and Neoplastic Tissues --; Investigations of Tissue Folates in Normal and Malignant Tissues --; Blood Cell Biopterin as an Indicator of Transplanation- Induced Hemopoiesis and Leukemic Cell Proliferation --; Assessment of Urinary Neopterin in the Early Diagnosis of Human Allograft Rejection --; Behaviour of Neopterin Levels in Patients with Haematological and Gynaecological Neoplasms --; Pteridines in Dictyostelium discoideum and Physarum polycephalum --; Biochemical and Chemotherapy Studies on BW 301U, a Novel Lipophilic 2,4-Diaminopyridopyrimidine Antifolate --; Toxicity of a Series of Antifolate Compounds in a Methotrexate-Resistant Celi Line --; Interaction of Methotrexate Poly(L-Lysine) with Transformed Hepatic Cells in Culture --; A Novel Technique for Producing Folate-Deficient Hepatica Cells --; Methotrexate Metabolism in Acute Lymphoblastic Leukemia --; Altered Methotrexate Sensitivity in Human Leukemic K562 Amino Acid Transport Mutant Cells --; Methotrexate and Methotrexate Polyglutamates in Erythrocytes After High-Dose Methotrexate --; Methotrexate Polyglutamates in Human Fibroblasts: Reversal of Antifolate Cytotoxicity --; Human Cells Resistant to Methotrexate: Cross Resistance and Collateral Sensitivity to the Nonclassical Antifolates Trimetrexate, Metoprine, Homofolic Acid and CB3717 --; Homology of Two Forms of Dihydrofolate Reductase in Human Leukaemic and L1210 Cells During Expression of Resistance to Methotrexate --; Adaptation of Folylpolyglutamates to Folate Deprivation in Mouse Hepatoma Cells --; Utilization and Loss of Reduced Folates by Human Fibroblasts in Vitro --; Factors Affecting Folate Polyglutamate Biosynthesis in Rat Liver --; Differential Binding of Folates but not Methotrexate (MTX) by Brush Border (BB) and Basal Lateral (BL) Membranes of Rat Renal Cortex --; Biosynthesis of Folate Derivatives in Ehrlich Ascites Carcinoma Cells Grown in Mice and in some Organs of the Host --; Variability of Thymidylate Synthetase in Ehrlich Carcinoma Cells and its Role in Resistance to 5-Fluorodeoxyuridine --; One-Carbon Metabolism in Human Lymphocytes --; Possible Mechanisms of Folate Catabolism --; The Intracellular Folate Pool: Studies of Kinetics and Functional Significance --; Intestinal Folate Transport. A pH-Dependent, Carrier- Mediated Process --; Effects of Folate Depletion on Growth and Survival of Human Cell Line K-562 in Culture --; Alterations in Folate Metabolism of the Rat Induced by Acute Ethanol Administration --; Participation of Pterins in the Control of Lymphocyte Transformation and Lymphoblast Proliferation --; The Pterin Component of the Molybdenum Cofactor (Molybdopterin): Relationship to Urothione --; Report on Presented Papers --; Author Index --; Subject Index --; Backmatter; restricted access; Issued also in print UR - https://doi.org/10.1515/9783111619453 UR - https://www.degruyter.com/isbn/9783111619453 UR - https://www.degruyter.com/document/cover/isbn/9783111619453/original ER -