| 000 | 05655nam a22013095i 4500 | ||
|---|---|---|---|
| 001 | 206969 | ||
| 003 | IT-RoAPU | ||
| 005 | 20221214233626.0 | ||
| 006 | m|||||o||d|||||||| | ||
| 007 | cr || |||||||| | ||
| 008 | 210830t20132013nju fo d z eng d | ||
| 020 |
_a9780691149783 _qprint |
||
| 020 |
_a9781400848461 _qPDF |
||
| 024 | 7 |
_a10.1515/9781400848461 _2doi |
|
| 035 | _a(DE-B1597)9781400848461 | ||
| 035 | _a(DE-B1597)474190 | ||
| 035 | _a(OCoLC)1004867046 | ||
| 040 |
_aDE-B1597 _beng _cDE-B1597 _erda |
||
| 050 | 4 | _aRC521 | |
| 072 | 7 |
_aSOC002000 _2bisacsh |
|
| 082 | 0 | 4 |
_a362.19683 _223 |
| 084 | _aonline - DeGruyter | ||
| 100 | 1 |
_aLock, Margaret _eautore |
|
| 245 | 1 | 4 |
_aThe Alzheimer Conundrum : _bEntanglements of Dementia and Aging / _cMargaret Lock. |
| 250 | _aCourse Book | ||
| 264 | 1 |
_aPrinceton, NJ : _bPrinceton University Press, _c[2013] |
|
| 264 | 4 | _c©2013 | |
| 300 |
_a1 online resource (328 p.) : _b12 line illus. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 505 | 0 | 0 |
_tFrontmatter -- _tContents -- _tAcknowledgments -- _tOrientations -- _tChapter 1. Making And Remaking Alzheimer Disease -- _tChapter 2. Striving to Standardize Alzheimer Disease -- _tChapter 3. Paths to Alzheimer Prevention -- _tChapter 4. Embodied Risk Made Visible -- _tChapter 5. Alzheimer Genes: Biomarkers of Prediction and Prevention -- _tChapter 6. Genome- Wide Association Studies: Back to the Future -- _tChapter 7. Living with Embodied Omens -- _tChapter 8. Chance Untamed and the Return of Fate -- _tChapter 9. Transcending Entrenched Tensions -- _tAfterword. Portraits from the Mind -- _tNotes -- _tIndex |
| 506 | 0 |
_arestricted access _uhttp://purl.org/coar/access_right/c_16ec _fonline access with authorization _2star |
|
| 520 | _aDue to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer's disease through early detection of pre-symptomatic biological changes in healthy individuals.Based on a meticulous account of the history of Alzheimer's disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure. | ||
| 530 | _aIssued also in print. | ||
| 538 | _aMode of access: Internet via World Wide Web. | ||
| 546 | _aIn English. | ||
| 588 | 0 | _aDescription based on online resource; title from PDF title page (publisher's Web site, viewed 30. Aug 2021) | |
| 650 | 0 |
_aAlzheimer's disease _xAge factors. |
|
| 650 | 0 | _aAlzheimer's disease. | |
| 650 | 0 |
_aBrain _xAging _xMolecular aspects. |
|
| 650 | 0 | _aDementia. | |
| 650 | 0 | _aElectronic books. | |
| 650 | 0 |
_aOlder people _xMental health. |
|
| 650 | 7 |
_aSOCIAL SCIENCE / Anthropology / General. _2bisacsh |
|
| 653 | _aAPOE. | ||
| 653 | _aAlois Alzheimer. | ||
| 653 | _aAlzheimer disease. | ||
| 653 | _aAlzheimer enterprise. | ||
| 653 | _aAlzheimer genetics. | ||
| 653 | _aAlzheimer prevention. | ||
| 653 | _aAlzheimer world. | ||
| 653 | _aAlzheimer's disease. | ||
| 653 | _aDNA samples. | ||
| 653 | _aDNA. | ||
| 653 | _aGWAS. | ||
| 653 | _aHuntington disease. | ||
| 653 | _aaging population. | ||
| 653 | _aaging populations. | ||
| 653 | _aaging societies. | ||
| 653 | _aamyloid cascade hypothesis. | ||
| 653 | _aamyloid cascade process. | ||
| 653 | _abehavioral changes. | ||
| 653 | _abiomarkers. | ||
| 653 | _abiosociality. | ||
| 653 | _abreast cancer. | ||
| 653 | _aclinical diagnosis. | ||
| 653 | _aclinical settings. | ||
| 653 | _acontrol samples. | ||
| 653 | _adementia. | ||
| 653 | _adiagnosis. | ||
| 653 | _adivination. | ||
| 653 | _aearly-onset. | ||
| 653 | _aenvironmental variables. | ||
| 653 | _aepidemiological research. | ||
| 653 | _aepidemiology. | ||
| 653 | _aepigenetics. | ||
| 653 | _aethnographic research. | ||
| 653 | _aexpert knowledge. | ||
| 653 | _afamily practice settings. | ||
| 653 | _agene function. | ||
| 653 | _agenes. | ||
| 653 | _agenetic testing. | ||
| 653 | _ageneticization. | ||
| 653 | _agenome-wide association studies. | ||
| 653 | _agenomics. | ||
| 653 | _aglobal economy. | ||
| 653 | _alate-onset. | ||
| 653 | _alocalization theory. | ||
| 653 | _amedical publications. | ||
| 653 | _amemory clinics. | ||
| 653 | _amemory loss. | ||
| 653 | _amicro-medical management. | ||
| 653 | _amild cognitive impairment. | ||
| 653 | _amolecular approach. | ||
| 653 | _amolecular biologists. | ||
| 653 | _amolecularization. | ||
| 653 | _aneuritic amyloid plaques. | ||
| 653 | _aneurofibrillary tangles. | ||
| 653 | _aneuroimaging. | ||
| 653 | _aprevention. | ||
| 653 | _aprodromal. | ||
| 653 | _apublic health. | ||
| 653 | _aresearch. | ||
| 653 | _athroughput technology. | ||
| 850 | _aIT-RoAPU | ||
| 856 | 4 | 0 | _uhttps://doi.org/10.1515/9781400848461?locatt=mode:legacy |
| 856 | 4 | 0 | _uhttps://www.degruyter.com/isbn/9781400848461 |
| 856 | 4 | 2 |
_3Cover _uhttps://www.degruyter.com/cover/covers/9781400848461.jpg |
| 942 | _cEB | ||
| 999 |
_c206969 _d206969 |
||