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| 001 | 248052 | ||
| 003 | IT-RoAPU | ||
| 005 | 20221215000335.0 | ||
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| 007 | cr || |||||||| | ||
| 008 | 221201t20191986gw fo d z ger d | ||
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_a9783110105971 _qprint |
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_a9783110871951 _qPDF |
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| 024 | 7 |
_a10.1515/9783110871951 _2doi |
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| 035 | _a(DE-B1597)9783110871951 | ||
| 035 | _a(DE-B1597)53793 | ||
| 035 | _a(OCoLC)1105862976 | ||
| 040 |
_aDE-B1597 _beng _cDE-B1597 _erda |
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| 050 | 4 |
_aQP93.5 _b.F537 1986 |
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_aMED008000 _2bisacsh |
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| 082 | 0 | 4 |
_a612.115 _223 |
| 084 | _aonline - DeGruyter | ||
| 245 | 0 | 0 |
_aFibrinogen. Proceedings/ Workshop on Fibrinogen. _nVol. 4, _pFibrin formation and Fibrinolysis ; April, 2–3, 1985, London, England / _chrsg. von D. A. Lane. |
| 250 | _aReprint 2019 | ||
| 264 | 1 |
_aBerlin ; _aBoston : _bDe Gruyter, _c[2019] |
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| 264 | 4 | _c©1986 | |
| 300 |
_a1 online resource (396 p.) : _bNum. figs. |
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| 336 |
_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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_aonline resource _bcr _2rdacarrier |
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_atext file _bPDF _2rda |
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_aFibrinogen. Proceedings/ Workshop on Fibrinogen ; _vVol. 4 |
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| 505 | 0 | 0 |
_tFrontmatter -- _tPreface -- _tContributors -- _tContents -- _tI. Synthesis And Assembly -- _tA scheme for the intracellular assembly of human fibrinogen -- _tEvidence that platelet and plasma fibrinogen have the same A-alpha chain gene product -- _tFibrinopeptide A and the phosphorylation of fibrinogen -- _tII. Structure and Function -- _tSize and shape of the fibrinogen molecule: crystalline forms of native and modified human fibrinogen -- _tThe C-terminal polymerisation domain of fibrinogen -- _tγ- Chain Crosslinking Of Fibrin At Dd-Trans Contact -- _tSoluble fibrin contains fibrin polymers of different molecular weight. Ultracentrifugation studies at 37°C -- _tRelationship of final thickness of fibrin fibers to maximal rate of assembly and to fibrinopeptide B release -- _tIII. Congenital Variants -- _tFibrinogen New York 1: The structural, functional, and genetic defects and an hypothesis of the role of fibrin in the regulation of coagulation and fibrinolysis -- _tFibrinogen Pontoise - a genetically abnormal fibrinogen with defective fibrin polymerisation but normal fibrinopeptide release -- _tFibrinogen Milano I: Abnormal fibrin polymerization related to a carboxy-terrainal defect of the γ-chain (γ-330 Asp Val) -- _tFibrinogen "Bergamo I" (Λα 16 Arg - Cys): Alternative methods for structure elucidation -- _tScreening small plasma samples by HPLC for abnormalities of fibrinopeptide release -- _tIv. Fibrin(ogen) And Fibrinolysis -- _tOn the role of fibrin in the fibrinolytic system -- _tIsolation and characterisation of plasmic degradation products of fibrinogen by high-performance liquid chromatography -- _tThe acceleration of tissue-type plasminogen activator (t-PA)-mediated activation of plasminogen by fibrinogen cyanogen bromide fragments is species specific -- _tRole of fibrin polymerization in fibrinolysis: Comparison between polymerisable and unpolymerisable fibrins in the potentiating effect of plasminogen activation by tissue-type plasminogen activator (tpA) -- _tRole of fibrin and its degradation products in the activation of plasminogen by streptokinase and urokinase -- _tV. Interactions With Cells -- _tThe role of fibrinogen in platelet aggregation -- _tPlatelet-associated fibrinogen: Conformational change of fibrinogen induced by its adsorption to platelet-surface -- _tMigration of cultured endothelial cells in response to fibrinogen -- _tCharacteristics of the interactions of fibrinogen and soluble fibrin with cultured endothelial cells -- _tMechanism of fibrin-induced disorganisation of cultured human endothelial cells -- _tThe fibrinogen: red cell interaction and its influence on blood rheology -- _tHaemorheologic effects of plasmin and thrombininduced fibrinogen derivatives: An in vitro study -- _tBinding of human fibrinogen to streptococci and its role in streptococcal pathogenicity -- _tVI. Assays To Fibrin(ogen) Fragments And Their Use -- _tDiscrimination between fibrin and fibrinogen by a monoclonal antibody against a synthetic hexapeptide representing the amino-terminus of the alpha-chain of fibrin -- _tA new enzyme immunoassay of fibrin(ogen) degradation products in plasma using a monoclonal antibody -- _tFibrin(ogen) degradation products. Determination using a monoclonal anti D neo antibody. Advantages in clinical investigation -- _tA monoclonal antibody, specific for human fibrinogen and fibrinopeptide A-containing fragments. Its application in an enzyme-immunoassay for fibrinogen degradation products, suitable for use in plasma -- _tA monoclonal antibody against the CNBr-peptide F-CB3 of the Aα-chain of human fibrinogen -- _tClinical aspects of fibrin formation and fibrinolysis measured with monoclonal antibodies against D-dimer -- _tFibrinogen derivatives in acute stroke -- _tVII. Fibrin(ogen) And Disease Pathology -- _tTriggering of the extrinsic blood coagulation system -- _tExtravascular fibrin formation and fibrinolysis in a model of inflammation accompanying cellular hypersensitivity -- _tExtra-vascular fibrin deposition in cellular hypersensitivity - the role of T lymphocyte-macrophage interactions -- _tFibrinolytic studies in disorders of connective tissue -- _tSoluble fibrin/fibrinogen related antigen in human intima in relation to atherogenesis -- _tFibrinogen as a possible risk factor for IHD in the Caerphilly study -- _tVIII. Appendix: Data On Fibrinogen -- _tFibrinogen amino acid sequences -- _tAuthor Index -- _tSubject Index -- _tBackmatter |
| 506 | 0 |
_arestricted access _uhttp://purl.org/coar/access_right/c_16ec _fonline access with authorization _2star |
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| 530 | _aIssued also in print. | ||
| 538 | _aMode of access: Internet via World Wide Web. | ||
| 546 | _aIn German. | ||
| 588 | 0 | _aDescription based on online resource; title from PDF title page (publisher's Web site, viewed 01. Dez 2022) | |
| 650 | 0 |
_aFibrin _vCongresses. |
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| 650 | 0 |
_aFibrinogen _vCongresses. |
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| 650 | 0 |
_aFibrinolysis _vCongresses. |
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| 650 | 7 |
_aMEDICAL / Biochemistry. _2bisacsh |
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| 700 | 1 |
_aBeck, Eugene A. _eautore |
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| 700 | 1 |
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| 700 | 1 |
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| 700 | 1 |
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_aBode, W. _eautore |
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| 700 | 1 |
_aBonnet, P. _eautore |
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_aCaen, J.P. _eautore |
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| 700 | 1 |
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| 700 | 1 |
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| 700 | 1 |
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| 700 | 1 |
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_aEtherington, M.D. _eautore |
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| 700 | 1 |
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_aFurlan, Miha _eautore |
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| 700 | 1 |
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| 700 | 1 |
_aGaffney, P.J. _eautore |
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| 700 | 1 |
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| 700 | 1 |
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| 700 | 1 |
_aWeimar, B. _eautore |
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| 700 | 1 |
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| 700 | 1 |
_aYu, Sharon _eautore |
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| 850 | _aIT-RoAPU | ||
| 856 | 4 | 0 | _uhttps://doi.org/10.1515/9783110871951 |
| 856 | 4 | 0 | _uhttps://www.degruyter.com/isbn/9783110871951 |
| 856 | 4 | 2 |
_3Cover _uhttps://www.degruyter.com/document/cover/isbn/9783110871951/original |
| 942 | _cEB | ||
| 999 |
_c248052 _d248052 |
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